Methylene Blue IV
***Needs 2 weeks to order...Please book 2 week out.
- 1 hr1 hour
- 125 US dollars$125
- Ridge Road
Common Use: Prevent and reverse aging Cognitive function: Alzheimer's, Parkinson's, Huntington's disease, Lyme disease Methylene blue (MB), is both a bioactive substance and a blue dye. It was FDA approved for its treatment of methemoglobinemia, but has been used for decades for a variety of purposes. One of the major purposes in anti-aging is sirtuin activation. Sirtuin activation is now being seen as one of the major ways to increase healthspan. In clinical trials we see that Methylene Blue treatment can help activate sirtuins. In one trial it increased NAD(+)/NADH ratio in hepatocytes, up-regulated SIRT1, and thereby decreased PGC-1α acetylation. In addition, hepatic mitochondrial DNA contents and oxygen consumption rates were enhanced. Methylene Blue treatment also notably activated AMPK, CPT-1 and PPARα: the AMPK activation relied on SIRT1. There’s a growing body of evidence that it can also directly improve cellular and mitochondrial function and decrease the production of proteins linked to Alzheimer’s. It is also being studied for its potential to inhibit monoamine oxidase (MAO), nitric oxide (NO) synthase, and guanylate cyclase.
656 Ridge Road, Webster, NY, USA